Research exploring viscoelastic properties of cells
Discover the groundbreaking research by Carolin Grandy published in SPIE Proceedings, who explored the viscoelastic properties of cells on micropatterns using Sensific’s cutting-edge ODIN VELOMIR system.
This innovative study, showcased at SPIE BiOS 2022, highlights how cells are incredibly responsive to their mechanical and structural surroundings through mechanosensing.
Micropatterning offers precise control over cellular forces by altering cell shapes. The VELOMIR sensor excels in capturing these adaptations and changes in viscoelastic properties with unmatched detail and over extended periods.
With live cell measurements taken at an impressive 3000 frames per second for 10 minutes, this technology reveals significant differences in passive microrheology measurements of mouse embryonic fibroblasts.
Reference: C. Grandy, J. Pfeil, F. Port, K.-E. Gottschalk, O. Marti, “Showing differences in viscoelastic properties of cells growing on micropattern by using very long-time high speed microrheology as a new way to measure cell mechanics,” Proc. SPIE 11971, High-Speed Biomedical Imaging and Spectroscopy VII, 119710B (2 March 2022)