An introduction to the ODIN system
At SPIE Bios 2019, Daniel introduced Sensific´s ODIN system, published in SPIE Proceedings. Perfect for microrheology and flow cytometry, our technology excels in measuring cell mechanics and identifying cell types with exceptional accuracy.
Traditional high-speed cameras rely on buffering to achieve high frame rates, but our innovative system combines a high-speed CMOS image sensor, FPGA, and pulsed LED illumination. This setup performs real-time image transformation on the FPGA, reducing data size and noise without losing crucial information.
Our modular analysis toolkit enables complete, on-the-fly analysis directly on the FPGA, eliminating the need for buffering and allowing continuous high-frame-rate measurements. This capability allows us to analyze large numbers of objects at high throughput rates in microfluidic devices.
The power of our ODIN system is demonstrated with the analysis of diluted whole blood and a sorting application that observes multiple regions of interest simultaneously, enabling particle analysis before and after manipulation.
Reference: D. Geiger, T. Neckernuss, J. Pfeil, P. Schwilling, O. Marti, “High throughput optical analysis and sorting of cells and particles in microfluidic systems,” Proc. SPIE 10875, Microfluidics, BioMEMS, and Medical Microsystems XVII, 1087517 (4 March 2019)